Laser shot noise can be reduced using optical squeezing techniques, and we achieved a record level of squeezing in the short-wavelength band using picosecond pulses. This light source was used for quantum-enhanced stimulated Raman scattering microscopy.
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The sensitivity of conventional stimulated Raman scattering microscopy is limited by laser shot noise, but we overcome this fundamental limit using quantum enhancement techniques.
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Three-photon fluorescence imaging enables deep-tissue imaging, and we combined it with lifetime imaging to further extend the imaging depth.
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